VEZF1
Function
Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.
Involvement in disease
Cardiomyopathy, dilated, 1OO
CMD1OO
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. CMD1OO inheritance is autosomal dominant.
None
The disease may be caused by variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Tissue Specificity
Ubiquitously expressed. Highest levels in skeletal muscle and kidney.
Cellular localization
- Nucleus
Alternative names
DB1, ZNF161, VEZF1, Vascular endothelial zinc finger 1, Putative transcription factor DB1, Zinc finger protein 161