VPREB1
Function
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.
Sequence Similarities
Belongs to the immunoglobulin superfamily.
Tissue Specificity
Only expressed by pre-B-cells.
Cellular localization
- Endoplasmic reticulum
Alternative names
CD179a, VPREB, VPREB1, Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V(pre)B protein, VpreB protein