VTI1B

Function

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.

Sequence Similarities

Belongs to the VTI1 family.

Tissue Specificity

Expressed in all tissues examined.

Cellular localization

• Early endosome membrane
• Single-pass type IV membrane protein
• Late endosome membrane
• Single-pass type IV membrane protein
• Lysosome membrane
• Cytoplasmic granule
• Recycling endosome membrane
• Single-pass type IV membrane protein

Alternative names

VTI1, VTI1L, VTI1L1, VTI2, VTI1B, Vesicle transport through interaction with t-SNAREs homolog 1B, Vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1

Database links

swissprot:Q9UEU0 omim:603207 genbank:BC003142 entrezGene:10490