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WFIKKN2

Function

Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).

Sequence Similarities

Belongs to the WFIKKN family.

Tissue Specificity

Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.

Cellular localization

Alternative names

GASP1, WFIKKNRP, UNQ9235/PRO31996, WFIKKN2, Growth and differentiation factor-associated serum protein 1, WFIKKN-related protein, GASP-1, hGASP-1

swissprot:Q8TEU8 omim:610895 entrezGene:124857