WNT11

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.

Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.

Belongs to the Wnt family.

Expressed in fetal lung, kidney, adult heart, liver, skeletal muscle, and pancreas.

• Secreted
• Extracellular space
• Extracellular matrix

Protein Wnt-11, WNT11

• entrezGene:7481
• omim:603699
• swissprot:O96014

Proteins

Oncology

39179Da