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WSB2

Domain

The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.

Function

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Pathway

Protein modification; protein ubiquitination.

Alternative names

WD repeat and SOCS box-containing protein 2, WSB-2, CS box-containing WD protein, WSB2

swissprot:Q9NYS7 entrezGene:55884