ZBTB20
Function
May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
Involvement in disease
Primrose syndrome
PRIMS
A disease characterized by macrocephaly, intellectual disability, disturbed behavior, dysmorphic facial features, ectopic calcifications, large calcified ear auricles, and progressive muscle wasting.
None
The disease is caused by variants affecting the gene represented in this entry.
Post-translational modifications
Sumoylated with SUMO1.
Tissue Specificity
Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver.
Cellular localization
- Nucleus
Alternative names
DPZF, ZNF288, ZBTB20, Zinc finger and BTB domain-containing protein 20, Dendritic-derived BTB/POZ zinc finger protein, Zinc finger protein 288