JavaScript is disabled in your browser. Please enable JavaScript to view this website.

ZCCHC12

Function

Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity).

Sequence Similarities

Belongs to the ZCCHC12 family.

Alternative names

SIZN1, ZCCHC12, Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1

swissprot:Q6PEW1 omim:300701 entrezGene:170261