ZHX3
Function
Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.
Sequence Similarities
Belongs to the ZHX family.
Tissue Specificity
Widely expressed. High expression in kidney. Expressed during osteogenic differentiation.
Cellular localization
- Nucleus
Alternative names
KIAA0395, TIX1, ZHX3, Zinc fingers and homeoboxes protein 3, Triple homeobox protein 1, Zinc finger and homeodomain protein 3