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Zinc finger homeobox protein 4

Function

May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation.

Involvement in disease

A chromosomal aberration involving ZFHX4 is found in one patient with ptosis. Translocation t(1;8)(p34.3;q21.12).

Sequence Similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Tissue Specificity

Expressed in brain, skeletal muscle and liver. Very low expression in stomach.

Cellular localization

Alternative names

Zinc finger homeobox protein 4, Zinc finger homeodomain protein 4, ZFH-4, ZFHX4

swissprot:Q86UP3 entrezGene:79776 omim:606940