ZMAT3
Function
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.
Tissue Specificity
Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.
Cellular localization
- Nucleus
- Nucleus
- Nucleolus
Alternative names
PAG608, WIG1, ZMAT3, Zinc finger matrin-type protein 3, Zinc finger protein WIG-1, p53-activated gene 608 protein