ZNF589
Domain
The KRAB domain mediates interaction with TRIM28.
Function
May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.
Sequence Similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Tissue Specificity
Isoform 2 is widely expressed. Isoform 3 is only expressed in CD34(+) cells.
Cellular localization
- Nucleus
Alternative names
SZF1, ZNF589, Zinc finger protein 589, Stem cell zinc finger protein 1