ZNF593

The protein is largely disordered, with the exception of the zinc finger domain.

Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome (PubMed:32669547). Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity (PubMed:9115366).

Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.

Ubiquitous. Detected in spleen, prostate, testis, small intestine, colon and to a minor level in thymus and peripheral blood leukocytes.

• Nucleus
• Nucleolus
• Cytoplasm
• Shuttles between the nucleus and the cytoplasm.

ZT86, ZNF593, Zinc finger protein 593, Zinc finger protein T86

• entrezGene:51042
• swissprot:O00488

Proteins

15199Da