ZNF622
Function
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
Post-translational modifications
Phosphorylated by MELK. The phosphorylation may redirect the protein to the nucleus.
Ubiquitinated by HECTD1, leading to its degradation.
Sequence Similarities
Belongs to the REI1 family.
Tissue Specificity
Expressed in lung, kidney, spleen, liver and brain with lowest expression in kidney.
Cellular localization
- Cytoplasm
- Nucleus
Alternative names
ZPR9, ZNF622, Cytoplasmic 60S subunit biogenesis factor ZNF622, Zinc finger protein 622, Zinc finger-like protein 9