ZNF692
Function
May act as an transcriptional repressor for PCK1 gene expression, in turn may participate in the hepatic gluconeogenesis regulation through the activated AMPK signaling pathway.
Post-translational modifications
Phosphorylation at Ser-470 results in loss of DNA-binding activity.
Sequence Similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Tissue Specificity
Ubiquitous (PubMed:17097062). Highly expressed in brain, thymus and spleen (PubMed:17097062).
Cellular localization
- Nucleus
Alternative names
AREBP, ZFP692, ZNF692, Zinc finger protein 692, AICAR responsive element binding protein