Zyxin

Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).

Belongs to the zyxin/ajuba family.

• Cytoplasm
• Cytoplasm
• Cytoskeleton
• Nucleus
• Cell junction
• Focal adhesion
• Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.

Zyxin, Zyxin-2, ZYX

• entrezGene:7791
• omim:602002
• swissprot:Q15942

Proteins

Oncology

61277Da