Zyxin phospho S142
Function
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).
Sequence Similarities
Belongs to the zyxin/ajuba family.
Cellular localization
- Cytoplasm
- Cytoplasm
- Cytoskeleton
- Nucleus
- Cell junction
- Focal adhesion
- Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.
Alternative names
Zyxin, Zyxin-2, ZYX