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Non-coding RNAs guide

Non-coding RNAs (ncRNAs) are RNA molecules transcribed from the genome that do not encode proteins.

Non-coding RNAs play a big part in epigenetics regulation of gene expression in addition to their roles at the transcriptional and post-transcriptional level.

Recent studies have revealed that about 90% of the eukaryotic genome is transcribed. Interestingly, only 1–2% of these transcripts encode for proteins; the majority are transcribed as ncRNAs.

Non-coding RNAs can be divided into two main types: infrastructural and regulatory ncRNAs. Infrastructural ncRNAs seem to have a housekeeping role in translation and splicing and include species such as ribosomal, transfer and small nuclear RNAs. Regulatory ncRNAs are more interesting from an epigenetic point of view as they are involved in the modification of other RNAs. They can be further classified into the following:

  • Non-coding RNAs guide

    Non-coding RNAs (ncRNAs) are RNA molecules transcribed from the genome that do not encode proteins.