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Pathways

Our collection of major biological pathways spanning multiple research areas and diseases, designed to help you find high-quality products for your particular area of research.
  • Adult neurogenesis pathway

    Sun 06 Feb 2022

    This pathway, developed together with Gerd Kempermann from the Center for Regenerative Therapies in Dresden, shows the different processes contributing to adult neurogenesis in the olfactory bulb and hippocampus of the adult brain.

  • Alzheimer's disease pathway

    Mon 15 Apr 2024

    Learn about the prominent hypotheses behind the complex biochemistry of Alzheimer's disease with our downloadable pathway poster.

  • Autophagy in heart disease pathway

    Thu 22 Feb 2024

    This poster explores the contribution of autophagy to the development of heart disease.

  • Autophagy: Molecular mechanisms and overview

    Mon 26 Sep 2022

    Autophagy is a complex process by which dysfunctional cellular components are degraded inside the cell through the action of lysosomes. Here we review the key stages and processes involved in this pathway and the role of autophagy in different diseases.

  • Biomarkers in traumatic brain injury

    Mon 04 Mar 2024

    This poster explores the various components of a neuron and the proteins involved in traumatic brain injury.

  • Calcium signaling pathway

    Mon 21 Dec 2020

    This pathway highlights some of the key roles of calcium ions.

  • Cancer epigenetics pathway

    Thu 13 Oct 2022

    Our interactive poster highlights key epigenetic targets involved in the regulation of the biological processes critical to carcinogenesis.

  • Cancer immunotherapy and the PD-1/PD-L1 checkpoint pathway

    Mon 25 Jul 2022

    Read about the PD-1/PD-L1 pathway, its function in cancer, and how it is being used in immunotherapy.

  • Cancer immunotherapy: immune checkpoint poster

    Wed 05 Oct 2022

    This poster provides an overview of the cancer immunity cycle and how immunotherapy can be a powerful tool in the fight against cancer.

  • Cancer metabolism pathway

    Wed 30 Aug 2023

    This poster explores critical pathways involved in metabolic reprogramming and regulation of cancer cell metabolism.

  • Cell adhesion and metastasis pathway

    Fri 18 Aug 2023

    This pathway, created in collaboration with Jeroen Middelbeek, reviews the different steps of tumor formation and metastasis, from EMT to angiogenesis. We outline key factors influencing this process and highlight how the tumor cell environment may promote metastasis.

  • Chemokine signaling interactive pathway

    Mon 10 Oct 2022

    This pathway highlights the different classes of chemokines, their receptors, and how chemokine signaling activates the JAK/Stat, Ras, ERK, and Akt pathways.

  • Cholesterol metabolism pathway

    Thu 22 Feb 2024

    This poster explores the biosynthesis and regulation of cholesterol.

  • Complement cascade and its inhibitors

    Mon 17 May 2021

    Overview of three pathways leading to complement activation and some of their key inhibitors.

  • Cytokine network pathway

    Wed 09 Mar 2022

    Explore the cytokine network and find key products to support your research with our interactive poster.

  • Cytokine storm in COVID-19 pathway

    Thu 22 Feb 2024

    This poster describes the events of the cytokine storm following a COVID-19 infection.

  • DNA repair pathways poster

    Fri 23 Sep 2022

    This poster, created in collaboration with James Haber and Farokh Dotiwala (Brandeis University), and Michela Clerici (University of Milan, Bicocca), shows various DNA repair pathways, including homologous recombination, mismatch repair, nucleotide excision repair, DNA strand cross-link repair, and non-homologous end joining.

  • Epigenetics in acute myeloid leukemia

    Thu 13 Oct 2022

    This poster describes complex epigenetic mechanisms implicated in acute myeloid leukemia (AML), highlighting key targets and our broad range of proteomic tools against these targets, from recombinant antibodies and proteins to ELISA kits and cell lines.

  • Epigenetics modifications poster

    Thu 20 Apr 2023

    Our poster provides an extensive visual guide to epigenetic modifications to the core histones (H2A, H2B, H3, and H4) and DNA.

  • Epilepsy pathway

    Wed 28 Feb 2024

    This poster explores the contribution of neuroinflammation in the induction and exacerbation of epilepsy.