Sun 06 Feb 2022
This pathway, developed together with Gerd Kempermann from the Center for Regenerative Therapies in Dresden, shows the different processes contributing to adult neurogenesis in the olfactory bulb and hippocampus of the adult brain.
Mon 15 Apr 2024
Learn about the prominent hypotheses behind the complex biochemistry of Alzheimer's disease with our downloadable pathway poster.
Tue 30 Jul 2024
Find out about the biochemical mechanisms behind ALS with our pathway.
Wed 24 Jul 2024
Explore the major pathways implicated in autism spectrum disorder.
Thu 22 Feb 2024
This poster explores the contribution of autophagy to the development of heart disease.
Mon 26 Sep 2022
Autophagy is a complex process by which dysfunctional cellular components are degraded inside the cell through the action of lysosomes. Here we review the key stages and processes involved in this pathway and the role of autophagy in different diseases.
Mon 04 Mar 2024
This poster explores the various components of a neuron and the proteins involved in traumatic brain injury.
Mon 21 Dec 2020
This pathway highlights some of the key roles of calcium ions.
Thu 13 Oct 2022
Our interactive poster highlights key epigenetic targets involved in the regulation of the biological processes critical to carcinogenesis.
Mon 25 Jul 2022
Read about the PD-1/PD-L1 pathway, its function in cancer, and how it is being used in immunotherapy.
Wed 05 Oct 2022
This poster provides an overview of the cancer immunity cycle and how immunotherapy can be a powerful tool in the fight against cancer.
Wed 30 Aug 2023
This poster explores critical pathways involved in metabolic reprogramming and regulation of cancer cell metabolism.
Fri 18 Aug 2023
This pathway, created in collaboration with Jeroen Middelbeek, reviews the different steps of tumor formation and metastasis, from EMT to angiogenesis. We outline key factors influencing this process and highlight how the tumor cell environment may promote metastasis.
Mon 10 Oct 2022
This pathway highlights the different classes of chemokines, their receptors, and how chemokine signaling activates the JAK/Stat, Ras, ERK, and Akt pathways.
Thu 22 Feb 2024
This poster explores the biosynthesis and regulation of cholesterol.
Mon 17 May 2021
Overview of three pathways leading to complement activation and some of their key inhibitors.
Wed 09 Mar 2022
Explore the cytokine network and find key products to support your research with our interactive poster.
Thu 22 Feb 2024
This poster describes the events of the cytokine storm following a COVID-19 infection.
Fri 23 Sep 2022
This poster, created in collaboration with James Haber and Farokh Dotiwala (Brandeis University), and Michela Clerici (University of Milan, Bicocca), shows various DNA repair pathways, including homologous recombination, mismatch repair, nucleotide excision repair, DNA strand cross-link repair, and non-homologous end joining.
Thu 13 Oct 2022
This poster describes complex epigenetic mechanisms implicated in acute myeloid leukemia (AML), highlighting key targets and our broad range of proteomic tools against these targets, from recombinant antibodies and proteins to ELISA kits and cell lines.