Biomarkers in traumatic brain injury

Traumatic brain injury (TBI) occurs when the brain sustains sudden trauma from an external force, like a blow, significant jolt, or head penetration. Its severity varies, leading to temporary or permanent effects. Symptoms range from headaches to cognitive impairments such as confusion and memory loss, with severe cases causing coma. An important pathological feature of TBI is diffuse axonal injury, which damages axons in the brain's white matter, potentially leading to subsequent neurological conditions. Researchers are exploring biomarkers to predict outcomes for those affected by this injury.

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References

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