Schizophrenia is a severe mental disorder characterized by disorganized thinking and perception. Its development involves a complex interplay of factors such as genetics, neurotransmitter imbalances (including dopamine, serotonin, and glutamate), substance abuse, and early psychosocial experiences. Notably, dysregulation of glutamatergic receptor function, particularly the N-methyl-d-aspartate receptor (NMDAR) and metabotropic glutamate receptors (mGluRs), have been extensively researched in relation to schizophrenia.