Cardiovascular
All tools and resources for cardiovascular research
Cardiovascular diseases remain the leading cause of death worldwide, taking an estimated 17.9 million lives each year. The prevalence of cardiovascular diseases, including coronary heart disease, heart failure, atrial fibrillation and stroke, is forecast to rise significantly over the next 30 years. The complex pathology of cardiovascular diseases involves a multitude of factors, including atherosclerosis, inflammation, and genetic predispositions, which collectively contribute to the progression and severity of heart disease and stroke. Advancing our understanding of the mechanisms driving cardiovascular diseases is imperative.
Whether you’re researching angiogenesis, vasculature, or atherosclerosis, we share your passion for understanding the role of the cardiovascular system in disease development. That’s why we’ve collated our leading cardiovascular disease resources here. Our detailed pathway pages enable you to explore the biochemical cascades behind complex cardiovascular processes like autophagy in heart disease and fatty acid oxidation. In addition, our product recommendations can help you find the very best reagents to move your stroke research forward, including premium recombinant antibodies and diagnostic and prognostic ELISA kits.
Explore our cardiovascular pathways
Our collection of major biological pathways spanning multiple research areas and diseases are designed to help you find high-quality products for your particular area of research. Explore our top cardiovascular pathways below.
Autophagy in heart disease pathway
Autophagy is a fundamental cellular process that entails the breakdown and recycling of defective components within the cell and is crucial for maintaining cellular equilibrium. This self-contained mechanism selectively eliminates misfolded proteins and worn-out organelles. This poster explores the contribution of autophagy to the development of heart disease.
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Fatty acid oxidation
Fatty acids provide highly efficient energy storage, delivering more energy per gram than carbohydrates like glucose. In tissues with high energy requirement, such as heart, up to 50–70% of energy, in the form of ATP production, comes from fatty acid (FA) beta-oxidation. Explore our pathway, where we describe how fatty acids are broken down and used to generate ATP.
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