Mast cell markers
Your guide to identifying and studying mast cells.
Mast cells play a central role in inflammatory and allergic reactions by releasing histamine.
CD23
Alternative names Low affinity immunoglobulin epsilon Fc receptor, Fc epsilon RII, FCER2, CLEC4J
Low affinity receptor for IgE, ligand for CD19, CD21 and CD81. Essential for B-cell growth and differentiation. In soluble form, functions as mitogenic growth factor.
We recommend
CD117
Alternative names c-kit, KIT, SCFR
Receptor tyrosine kinase which phosphorylates multiple intracellular proteins that play a role in proliferation, differentiation, migration, and apoptosis.
We recommend
Anti-c-Kit antibody [EPR25707-134] (ab283653)
CD203c
Alternative names ENPP3, B10, PDNP3
Limits mast cell and basophil responses during inflammation, expression upregulated when these cells are activated by an allergy. Enzyme catalyzing hydrolysis of deoxynucleotides, nucleotide sugars and NAD.
We recommend
Anti-ENPP3/B10 antibody [EPR27349-72] (ab308453)
CD64
Alternative names IgG Fc receptor I, FCGR1A, IGFR1
Binds to the Fc region of IgG with high affinity, expression induced by bacterial infection.
We recommend
Anti-CD64 antibody [EPR4623] (ab109449)
Browse CD64 antibodies for flow cytometry
Further reading
See the below references for a list of relevant reviews.
References
View 3 references for Further reading
References
Further reading
Hauswirth, A. W., et al. Expression of cell surface antigens on mast cells: mast cell phenotyping Methods Mol. Biol. 315 ,77-90 (2006)
Sánchez-Muñoz, L., Teodósio, C., Morgado, J. M., Escribano, L. Immunophenotypic characterization of bone marrow mast cells in mastocytosis and other mast cell disorders Methods Cell Biol. 103 ,333-359 (2011)
Murphy, K. Janeway's Immunobiology Garland Science , (2012)