Mast cell markers

Your guide to identifying and studying mast cells.

Mast cells play a central role in inflammatory and allergic reactions by releasing histamine.

CD23

Alternative names Low affinity immunoglobulin epsilon Fc receptor, Fc epsilon RII, FCER2, CLEC4J

Low affinity receptor for IgE, ligand for CD19, CD21 and CD81. Essential for B-cell growth and differentiation. In soluble form, functions as mitogenic growth factor.

We recommend

Browse all CD23 antibodies

CD117

Alternative names c-kit, KIT, SCFR

Receptor tyrosine kinase which phosphorylates multiple intracellular proteins that play a role in proliferation, differentiation, migration, and apoptosis.

We recommend

Anti-c-Kit antibody [EPR25707-134] (ab283653)

CD203c

Alternative names ENPP3, B10, PDNP3

Limits mast cell and basophil responses during inflammation, expression upregulated when these cells are activated by an allergy. Enzyme catalyzing hydrolysis of deoxynucleotides, nucleotide sugars and NAD.

We recommend

Anti-ENPP3/B10 antibody [EPR27349-72] (ab308453)

CD64

Alternative names IgG Fc receptor I, FCGR1A, IGFR1

Binds to the Fc region of IgG with high affinity, expression induced by bacterial infection.

We recommend

Anti-CD64 antibody [EPR4623] (ab109449)

Browse CD64 antibodies for flow cytometry

Further reading

See the below references for a list of relevant reviews.

References

View 3 references for Further reading

References

Further reading

Hauswirth, A. W., et al. Expression of cell surface antigens on mast cells: mast cell phenotyping  Methods Mol. Biol.   315 ,77-90 (2006)

Sánchez-Muñoz, L., Teodósio, C., Morgado, J. M., Escribano, L. Immunophenotypic characterization of bone marrow mast cells in mastocytosis and other mast cell disorders  Methods Cell Biol103 ,333-359 (2011)

Murphy, K. Janeway's Immunobiology  Garland Science , (2012)