Overview

  • Product name

    Enalapril, Angiotensin-converting enzyme inhibitor
  • Description

    Angiotensin-converting enzyme inhibitor
  • Biological description

    Angiotensin-converting enzyme (ACE) inhibitor. Modulates pathways leading to hypertension and related dementia. Has anti-cancer potential. Orally active.
  • Purity

    > 98%
  • CAS Number

    75847-73-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-1-[(2S)-2-[[(2R)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
  • Molecular weight

    376.45
  • Molecular formula

    C20H28N2O5
  • PubChem identifier

    5362032
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Claassen K  et al. A detailed physiologically based model to simulate the pharmacokinetics and hormonal pharmacodynamics of enalapril on the circulating endocrine Renin-Angiotensin-aldosterone system. Front Physiol 4:4 (2013). Read more (PubMed: 23404365) »
  • Purclutepe O  et al. Enalapril-induced apoptosis of acute promyelocytic leukaemia cells involves STAT5A. Anticancer Res 32:2885-93 (2012). Read more (PubMed: 22753752) »
  • Kelly JG & O'Malley K Clinical pharmacokinetics of the newer ACE inhibitors. A review. Clin Pharmacokinet 19:177-96 (1990). Read more (PubMed: 2203579) »

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