Overview

  • Product name

  • Description

    Rabbit polyclonal to ENL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human ENL aa 325-375.
    Database link: NP_005925.2

  • Positive control

    • Human skin carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab111864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/250.

Target

  • Function

    Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.
  • Involvement in disease

    Note=A chromosomal aberration involving MLLT1 is associated with acute leukemias. Translocation t(11;19)(q23;p13.3) with MLL/HRX. The result is a rogue activator protein.
  • Sequence similarities

    Contains 1 YEATS domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • ENL antibody
    • ENL_HUMAN antibody
    • LTG19 antibody
    • MLLT1 antibody
    • Myeloid/lymphoid or mixed lineage leukemia trithorax (Drosophila) antibody
    • Protein ENL antibody
    • YEATS domain containing protein 1 antibody
    • YEATS domain-containing protein 1 antibody
    • YEATS1 antibody
    see all

Images

  • ab111864 at 1/250 dilution staining ENL in Human skin carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining

References

ab111864 has not yet been referenced specifically in any publications.

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