Overview

  • Product name

    ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist
  • Description

    Selective protease-activated receptor 2 (PAR2) anatagonist
  • Biological description

    Selective protease-activated receptor 2 (PAR2) antagonist (IC50 = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.
  • Purity

    > 99%
  • CAS Number

    789488-77-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lohman RJ  et al. An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. FASEB J 26:2877-87 (2012). Read more (PubMed: 22467762) »
  • Crilly A  et al. Immunomodulatory role of proteinase-activated receptor-2. Ann Rheum Dis 71:1559-66 (2012). Read more (PubMed: 22563031) »
  • Kelso EB  et al. Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. J Pharmacol Exp Ther 316:1017-24 (2006). Read more (PubMed: 16260582) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141699.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up