Overview

  • Product name

    Enocitabine, DNA replication inhibitor.
  • Description

    Nucleoside analog. DNA replication inhibitor.
  • Biological description

    Nucleoside analog and DNA replication inhibitor. Inhibits replication of human cytomegalovirus in vitro. Antitumor and antiviral agent. Active in vitro and in vivo.
  • Purity

    > 95%
  • CAS Number

    55726-47-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[1-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide

  • Molecular weight

    565.78
  • Molecular formula

    C31H55N3O6
  • PubChem identifier

    71734
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Oguro M  et al. [In vitro effect of combined use of BH-AC and nitrosourea derivatives against adriamycin-resistant human leukemia cell line]. Gan To Kagaku Ryoho 18:2403-8 (1991). Read more (PubMed: 1952959) »
  • Nakamura K  et al. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol 31:141-7 (1990). Read more (PubMed: 1696958) »
  • Higashigawa M  et al. Incorporation of N4-behenoyl-1-beta-D-arabinofuranosylcytosine into DNA as 1-beta-D-arabinofuranosylcytosine. Med Oncol Tumor Pharmacother 5:265-71 (1988). Read more (PubMed: 2848163) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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