Product nameAnti-ENOX2/tNOX antibody
See all ENOX2/tNOX primary antibodies
DescriptionRabbit polyclonal to ENOX2/tNOX
Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment corresponding to Human ENOX2/tNOX aa 200-610 (C terminal).
Database link: Q16206
- WB: Extracts from MCF7, THP-1, SW480, Jurkat, SKOV3, mouse liver, kidney and ovary and rat liver. ICC/IF: U20S cells.
Previously labelled as ENOX2.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab210751 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 70 kDa.|
|ICC/IF||1/50 - 1/100.|
|IHC-P||1/50 - 1/200.|
FunctionMay be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
Tissue specificityFound in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Found on the cell borders of renal, kidney and ovarian carcinomas but not on the borders of surrounding non-cancerous stromal cells.
Sequence similaritiesBelongs to the ENOX family.
Contains 1 RRM (RNA recognition motif) domain.
Cellular localizationCell membrane. Secreted > extracellular space. Extracellular and plasma membrane-associated.
- Information by UniProt
- APK1 antibody
- APK1 antigen antibody
- COVA1 antibody
All lanes : Anti-ENOX2/tNOX antibody (ab210751) at 1/500 dilution
Lane 1 : Extracts from MCF7 cell line
Lane 2 : Extracts from THP-1 cell line
Lane 3 : Extracts from SW480 cell line
Lane 4 : Extracts from Jurkat cell line
Lane 5 : Extracts from SKOV3 cell line
Lane 6 : Extracts from mouse liver
Lane 7 : Extracts from mouse kidney
Lane 8 : Extracts from mouse ovary
Lane 9 : Extracts from rat liver
Predicted band size: 70 kDa
Immunofluorescence analysis of MCF7 cells labeling ENOX2/tNOX with ab210751 at a 1/50 dilution (red). Nuclei were counterstained with DAPI (blue).
Immunofluorescence analysis of U20S cells labeling ENOX2/tNOX with ab210751 at a 1/50 dilution (red). Nuclei were counterstained with DAPI (blue).
ab210751 has not yet been referenced specifically in any publications.