• Product name

    Anti-ENPP3/B10 antibody [NP4D6]
    See all ENPP3/B10 primary antibodies
  • Description

    Mouse monoclonal [NP4D6] to ENPP3/B10
  • Host species

  • Specificity

    The mouse monoclonal antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
  • Tested applications

    Suitable for: ICC/IF, IHC-Fr, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human ENPP3/B10.

  • General notes

     This product was previously labelled as ENPP3




Our Abpromise guarantee covers the use of ab90754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-Fr 1/100. PubMed: 23225236
Flow Cyt Use a concentration of 1 - 5 µg/ml.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.



  • Function

    Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.
  • Tissue specificity

    Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors.
  • Sequence similarities

    Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
    Contains 2 SMB (somatomedin-B) domains.
  • Post-translational

    N-glycosylation is necessary for correct trafficking to the apical surface, but is not the apical targeting signal.
    It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
  • Cellular localization

    Membrane. Secreted. Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • Alkaline phosphodiesterase I antibody
    • ARHR2 antibody
    • B10 antibody
    • CD203c antibody
    • CD203c antigen antibody
    • dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3) antibody
    • dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3) antibody
    • E NPP 3 antibody
    • E-NPP 3 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase 3 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 antibody
    • ENPP3 antibody
    • ENPP3_HUMAN antibody
    • gp130RB13 6 antibody
    • gp130RB136 antibody
    • M6S1 antibody
    • NPP1 antibody
    • NPP3 antibody
    • NPPase antibody
    • NPPS antibody
    • Nucleotide pyrophosphatase antibody
    • PC 1 antibody
    • PC-1 antibody
    • PCA1 antibody
    • PD Ibeta antibody
    • PD-Ibeta antibody
    • PDNP1 antibody
    • PDNP3 antibody
    • Phosphodiesterase I beta antibody
    • Phosphodiesterase I/nucleotide pyrophosphatase 3 antibody
    • phosphodiesterase i/nucleotide pyrophosphatase beta antibody
    see all


This product has been referenced in:

  • Aliagas E  et al. Ecto-nucleotidases distribution in human cyclic and postmenopausic endometrium. Purinergic Signal 9:227-37 (2013). IHC-Fr ; Human . Read more (PubMed: 23225236) »
See 1 Publication for this product

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