Enrofloxacin, Broad spectrum fluoroquinolone antibiotic agent (ab143393)

Overview

  • Product name

    Enrofloxacin, Broad spectrum fluoroquinolone antibiotic agent
  • Description

    Broad spectrum fluoroquinolone antibiotic agent
  • Biological description

    Broad spectrum fluoroquinolone antibiotic agent. Inhibits DNA gyrase (MIC values are 3 and 89 μM for gyrA mutant and qnr-containing E. coli respectively). Prevents DNA supercoiling and DNA synthesis. Orally active.
  • Purity

    > 98%
  • CAS Number

    93106-60-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
  • Molecular weight

    359.39
  • Molecular formula

    C19H22FN3O3
  • PubChem identifier

    71188
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Slightly soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Zampakou M  et al. Structure, antimicrobial activity, DNA- and albumin-binding of manganese(II) complexes with the quinolone antimicrobial agents oxolinic acid and enrofloxacin. J Inorg Biochem 121:88-99 (2013). Read more (PubMed: 23353085) »
  • Cengiz M  et al. In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. Vet Rec 172:474 (2013). Read more (PubMed: 23605176) »
  • Haritova A  et al. Comparative pharmacokinetics of enrofloxacin, danofloxacin, and marbofloxacin after intravenous and oral administration in Japanese quail (Coturnix coturnix japonica). J Avian Med Surg 27:23-31 (2013). Read more (PubMed: 23772453) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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