Anti-Enterokinase antibody (ab200691)
Key features and details
- Rabbit polyclonal to Enterokinase
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Enterokinase antibody -
Description
Rabbit polyclonal to Enterokinase -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Enterokinase aa 750-850.
Database link: P98073 -
Positive control
- A549, Raw264.7 and PC12 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.0975% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab200691 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500.
|
Notes |
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WB
1/500. |
Target
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Function
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. -
Tissue specificity
Intestinal brush border. -
Involvement in disease
Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 2 CUB domains.
Contains 2 LDL-receptor class A domains.
Contains 1 MAM domain.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain.
Contains 1 SRCR domain. -
Post-translational
modificationsThe chains are derived from a single precursor that is cleaved by a trypsin-like protease. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 5651 Human
- Entrez Gene: 19146 Mouse
- Entrez Gene: 288291 Rat
- Omim: 606635 Human
- SwissProt: P98073 Human
- SwissProt: P97435 Mouse
- Unigene: 149473 Human
- Unigene: 5184 Mouse
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Alternative names
- PRSS 7 antibody
- PRSS7 antibody
- Enterokinase antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab200691 has not yet been referenced specifically in any publications.