Anti-Enterovirus 71 antibody [10F0] (ab36367)
Key features and details
- Mouse monoclonal [10F0] to Enterovirus 71
- Suitable for: ICC/IF, Neutralising
- Isotype: IgG1
Overview
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Product name
Anti-Enterovirus 71 antibody [10F0]
See all Enterovirus 71 primary antibodies -
Description
Mouse monoclonal [10F0] to Enterovirus 71 -
Host species
Mouse -
Tested applications
Suitable for: ICC/IF, Neutralisingmore details -
Species reactivity
Reacts with: Enterovirus A71 -
Immunogen
Tissue, cells or virus corresponding to Enterovirus 71. Native Enterovirus 71
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Constituent: Ascites -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
10F0 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab36367 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
1/500 - 1/2000.
Fix with cold acetone for 10 minutes. Dilute antibody in PBS (pH 7.5 to pH 8.0) with 1% BSA. |
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Neutralising |
1/14.
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Notes |
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ICC/IF
1/500 - 1/2000. Fix with cold acetone for 10 minutes. Dilute antibody in PBS (pH 7.5 to pH 8.0) with 1% BSA. |
Neutralising
1/14. |
Target
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Relevance
Enterovirus 71 was first isolated in 1969. Since then it has been associated with sporadic cases of outbreaks in various parts of the world, including the U.S., Brazil, Europe, Austrailia, Malaysia, and Taiwan. Entervirus 71 infection may present itself much like other enterovirus infections, with symptoms ranging from asymptomatic to the presentation of rashes, diarrhea, colds, meningitis, encephalitis, hand to foot to mouth disease, myocarditis, or some combination of these syndromes. On the other hand, Enterovirus 71 may cause many unusal syndromes such as acute flaccid paralysis (similar to paralytic poliomyelitis), bulbar and brain encephalitis, Guillain Barre syndrome, and rapidly fatal pulmonary edema and hemmorrhage. -
Database links
- SwissProt: Q66478 Enterovirus A71
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Alternative names
- EV71 antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (18)
ab36367 has been referenced in 18 publications.
- Hsieh CF et al. 3,4-Dicaffeoylquinic Acid from the Medicinal Plant Ilex kaushue Disrupts the Interaction Between the Five-Fold Axis of Enterovirus A-71 and the Heparan Sulfate Receptor. J Virol 96:e0054221 (2022). PubMed: 35319229
- Zhang R et al. DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection. Front Cell Infect Microbiol 11:725392 (2021). PubMed: 34485180
- Sun M et al. Enterovirus A71 2B Inhibits Interferon-Activated JAK/STAT Signaling by Inducing Caspase-3-Dependent Karyopherin-α1 Degradation. Front Microbiol 12:762869 (2021). PubMed: 34992585
- Hsieh CF et al. Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors. Emerg Microbes Infect 9:1194-1205 (2020). PubMed: 32397909
- Cosset É et al. Modeling Poliovirus Infection Using Human Engineered Neural Tissue Enriched With Motor Neuron Derived From Embryonic Stem Cells. Front Cell Dev Biol 8:593106 (2020). PubMed: 33490061