Key features and details
- Mouse polyclonal to Enterovirus 71
- Suitable for: WB
- Isotype: IgG
Product nameAnti-Enterovirus 71 antibody
See all Enterovirus 71 primary antibodies
DescriptionMouse polyclonal to Enterovirus 71
SpecificityThis antibody is specific for the Protein VP1 cleaved chain of Genome polyprotein. The complete proteome is Human enterovirus 71 (Ev 71).
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Other species
Full length protein corresponding to Enterovirus 71 aa 1-297. The immunogen is EV71 Protein VP1. This cleaved chain is 297 aa in length and can be found from aa 566 to 862 in the complete proteome of human enterovirus 71 (EV 71)
GDRVADVIESSIGDSVSKALTPALPAPTGPDTQVSSHRLDTGKVPALQAA EIGASSNASDESMIETRCVLNSHSTAETTLDSFFSRAGLVGEIDLPLKGT TNPNGYANWDIDITGYAQMRRKVELFTYMRFDAEFTFVACTPTGRVVPQL LQYMFVPPGAPKPDSRDSLAWPTATNPSVFVKSSDPPAQVSVPFMSPASA YQWFYDGYPTFGEHKQEKDLEYGACPNNMMGTFSVRTVGSSKSEYSLVIR IYMRMKHVRAWIPRPMRNQNYLFKSNPNYAGDSIKPTGTSRTAITTL
Database link: Q66478
- Enterovirus 71 transfected 293T lysate.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab169442 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa.|
RelevanceEnterovirus 71 was first isolated in 1969. Since then it has been associated with sporadic cases of outbreaks in various parts of the world, including the U.S., Brazil, Europe, Austrailia, Malaysia, and Taiwan. Entervirus 71 infection may present itself much like other enterovirus infections, with symptoms ranging from asymptomatic to the presentation of rashes, diarrhea, colds, meningitis, encephalitis, hand to foot to mouth disease, myocarditis, or some combination of these syndromes. On the other hand, Enterovirus 71 may cause many unusal syndromes such as acute flaccid paralysis (similar to paralytic poliomyelitis), bulbar and brain encephalitis, Guillain Barre syndrome, and rapidly fatal pulmonary edema and hemmorrhage.
- EV71 antibody
ab169442 has been referenced in 4 publications.
- Zhang H et al. An infectious clone of enterovirus 71(EV71) that is capable of infecting neonatal immune competent mice without adaptive mutations. Emerg Microbes Infect 9:427-438 (2020). PubMed: 32079505
- Zhou B et al. Hsa-let-7c-5p augments enterovirus 71 replication through viral subversion of cell signaling in rhabdomyosarcoma cells. Cell Biosci 7:7 (2017). PubMed: 28101327
- Meng J et al. ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65. Cell Death Dis 8:e2866 (2017). PubMed: 28594402
- Qiu Y et al. Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals. Immunity 46:992-1004.e5 (2017). PubMed: 28636969