Key features and details
- Rabbit polyclonal to ENTPD5
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ENTPD5 antibody
See all ENTPD5 primary antibodies
DescriptionRabbit polyclonal to ENTPD5
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment within Human ENTPD5 aa 1-191. The exact sequence is proprietary. (NP_001240.1).
Database link: O75356
- Human kidney tissue; A431, H1299 and HeLa whole cell lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 89% Tris glycine, 10% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189406 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 48 kDa.|
|IHC-P||Use a concentration of 10 µg/ml.|
FunctionUridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Tissue specificityExpressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
PathwayProtein modification; protein glycosylation.
Sequence similaritiesBelongs to the GDA1/CD39 NTPase family.
modificationsN-glycosylated; high-mannose type.
Cellular localizationEndoplasmic reticulum lumen.
- Information by UniProt
- CD39 like 4 antibody
- AI196558 antibody
- AI987697 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling ENTPD5 with ab189406 at 10 µg/ml.
All lanes : Anti-ENTPD5 antibody (ab189406) at 1/1000 dilution
Lane 1 : A431 whole cell lysate
Lane 2 : H1299 whole cell lysate
Lane 3 : HeLa whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 48 kDa
10% SDS PAGE.
ab189406 has not yet been referenced specifically in any publications.