Key features and details
- Rabbit polyclonal to ENTPD5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ENTPD5 antibody
See all ENTPD5 primary antibodies
DescriptionRabbit polyclonal to ENTPD5
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 - 161 of Human ENTPD5 (NP_001240)
- 293T, A431, H1299, HeLa and HepG2 cell lysates
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab96067 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 48 kDa.|
FunctionUridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Tissue specificityExpressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
PathwayProtein modification; protein glycosylation.
Sequence similaritiesBelongs to the GDA1/CD39 NTPase family.
modificationsN-glycosylated; high-mannose type.
Cellular localizationEndoplasmic reticulum lumen.
- Information by UniProt
- CD39 like 4 antibody
- AI196558 antibody
- AI987697 antibody
ab96067 has not yet been referenced specifically in any publications.