Anti-Eosinophil derived neurotoxin antibody (ab238562)
Key features and details
- Rabbit polyclonal to Eosinophil derived neurotoxin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Eosinophil derived neurotoxin antibody
See all Eosinophil derived neurotoxin primary antibodies -
Description
Rabbit polyclonal to Eosinophil derived neurotoxin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Gorilla, Orangutan -
Immunogen
Recombinant full length protein corresponding to Human Eosinophil derived neurotoxin aa 1 to the C-terminus. Mature full-length chain without the signal peptide.
Database link: P10153 -
Positive control
- IHC-P: Human kidney and spleen tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purity >95% -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab238562 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P | (5) |
1/20 - 1/200.
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Notes |
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IHC-P
1/20 - 1/200. |
Target
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Relevance
Eosinophil derived neurotoxin (EDN) is a protein belonging to the ribonuclease (RNase) A superfamily. It has recently been found to have antiviral activity against respiratory syncytial virus and human immunodeficiency virus in vitro. -
Cellular localization
Lysosome (Probable). Cytoplasmic granule. Matrix of eosinophil's large specific granule. -
Database links
- Entrez Gene: 6036 Human
- Omim: 131410 Human
- SwissProt: P47785 Chimpanzee
- SwissProt: P47782 Gorilla
- SwissProt: P10153 Human
- SwissProt: P47784 Orangutan
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Alternative names
- Ear4 antibody
- EC=3.1.27.5 antibody
- EDN antibody
see all
Images
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Paraffin-embedded human kidney tissue stained for Eosinophil derived neurotoxin using ab238562 at 1/100 dilution in immunohistochemical analysis.
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Paraffin-embedded human spleen tissue stained for Eosinophil derived neurotoxin using ab238562 at 1/100 dilution in immunohistochemical analysis.
After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized tissue using an HRP conjugated SP system.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab238562 has not yet been referenced specifically in any publications.