Overview

  • Product name

  • Description

    Rabbit polyclonal to EPCR/CD201
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    The immunogen is recombinant fragment contain a sequence corresponding to a region within amino acids 121 and 240 of EPCR(NP_006395)

  • Positive control

    • HeLa, JC and BCL-1 whole cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab151403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.

Target

  • Function

    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
  • Tissue specificity

    Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
  • Post-translational
    modifications

    N-glycosylated.
    A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activated protein C receptor antibody
    • APC receptor antibody
    • APCR antibody
    • bA42O4.2 antibody
    • CCCA antibody
    • CCD41 antibody
    • CD201 antibody
    • CD201 antigen antibody
    • cell cycle, centrosome-associated protein antibody
    • Cell cycle, centrosome-associated protein antibody
    • centrocyclin antibody
    • Endothelial cell protein C receptor antibody
    • Endothelial protein C receptor antibody
    • EPCR antibody
    • EPCR_HUMAN antibody
    • MGC23024 antibody
    • PROCR antibody
    • Protein C receptor, endothelial antibody
    see all

Images

  • All lanes : Anti-EPCR/CD201 antibody (ab151403) at 1/1000 dilution

    Lane 1 : JC whole cell lysate
    Lane 2 : BCL-1 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 27 kDa



    12 % SDS-PAGE
  • Anti-EPCR/CD201 antibody (ab151403) at 1/1000 dilution + HeLa whole cell
    lysate at 30 µg

    Predicted band size: 27 kDa



    12 % SDS-PAGE

References

This product has been referenced in:

  • Wang Q  et al. EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis in vitro through activating ERK1/2 and AKT in a PAR1-dependent manner. Oncol Lett 16:1565-1570 (2018). Read more (PubMed: 30008838) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151403.
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