Anti-Eph receptor A3 antibody (ab110465)
Key features and details
- Rabbit polyclonal to Eph receptor A3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Eph receptor A3 antibody
See all Eph receptor A3 primary antibodies -
Description
Rabbit polyclonal to Eph receptor A3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
A synthesized peptide derived from an internal region of Human Eph receptor A3 (UniProt ID: P29320).
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Positive control
- Extracts from 293 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab110465 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab110465 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 110 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 110 kDa. |
Target
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Function
Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function. -
Tissue specificity
Widely expressed. Highest level in placenta. -
Involvement in disease
Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500]. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Contains 2 fibronectin type-III domains.
Contains 1 protein kinase domain.
Contains 1 SAM (sterile alpha motif) domain. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2042 Human
- Entrez Gene: 13837 Mouse
- Entrez Gene: 29210 Rat
- Omim: 179611 Human
- SwissProt: P29320 Human
- SwissProt: P29319 Mouse
- SwissProt: O08680 Rat
- Unigene: 123642 Human
see all -
Alternative names
- AW492086 antibody
- Cek4 antibody
- EC 2.7.10.1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab110465 has been referenced in 1 publication.
- Xu H et al. EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis. Biosci Rep 39:N/A (2019). PubMed: 31262977