Overview

  • Product name
    Anti-Eph receptor A3 antibody - N-terminal
    See all Eph receptor A3 primary antibodies
  • Description
    Rabbit polyclonal to Eph receptor A3 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Eph receptor A3 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. NM_005233.5, NP_005224.2.
    Database link: P29320

  • Positive control
    • Human Small Intestine tissue; HL-60 and 293 cell line ysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab174792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 110 kDa.

Target

  • Function
    Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.
  • Tissue specificity
    Widely expressed. Highest level in placenta.
  • Involvement in disease
    Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Cellular localization
    Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AW492086 antibody
    • Cek4 antibody
    • EC 2.7.10.1 antibody
    • EK4 antibody
    • End3 antibody
    • Eph receptor A3 antibody
    • EPH-like kinase 4 antibody
    • EPH-like tyrosine kinase 1 antibody
    • EPHA3 antibody
    • EPHA3_HUMAN antibody
    • Ephrin receptor EphA3 antibody
    • Ephrin type-A receptor 3 antibody
    • ETK 1 antibody
    • ETK antibody
    • ETK1 antibody
    • HEK 4 antibody
    • HEK antibody
    • HEK4 antibody
    • Human embryo kinase 1 antibody
    • Human embryo kinase antibody
    • Mek4 antibody
    • MGC109882 antibody
    • Receptor tyrosine kinase HEK antibody
    • Testicular tissue protein Li 64 antibody
    • Tyro 4 antibody
    • Tyro4 antibody
    • TYRO4 protein tyrosine kinase antibody
    • Tyrosine protein kinase receptor ETK 1 antibody
    • Tyrosine-protein kinase receptor ETK1 antibody
    • Tyrosine-protein kinase TYRO4 antibody
    see all

Images

  • All lanes : Anti-Eph receptor A3 antibody - N-terminal (ab174792) at 1/100 dilution

    Lane 1 : HL-60 cell line lysate
    Lane 2 : 293 cell line lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 110 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human small intestine tissue labeling Eph receptor A3 with ab174792 at 5 μg/ml.

References

ab174792 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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