Key features and details
- Rabbit polyclonal to Eph receptor B1 + Eph receptor B2
- Suitable for: IHC-P, ELISA, WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Eph receptor B1 + Eph receptor B2 antibody
See all Eph receptor B1 + Eph receptor B2 primary antibodies
DescriptionRabbit polyclonal to Eph receptor B1 + Eph receptor B2
Tested applicationsSuitable for: IHC-P, ELISA, WB, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic non-phosphopeptide derived from human Eph receptor B1 from around the phosphorylation site of tyrosine 594 (K-I-YP-I-D).
- Extracts from HepG2 cells, HuvEc cells.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab61765 in the following tested applications.
|IHC-P||1/50 - 1/100.|
|WB||1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 110 kDa).|
|ICC/IF||1/500 - 1/1000.|
RelevanceEphrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
Cellular localizationMembrane; Single-pass type I membrane protein.
- EPH B1 antibody
- EPH B2 antibody
- Eph tyrosine kinase 2 antibody
HuvEc cells stained wth ab61765 at 1/500 - 1/1000, with and without the immunising peptide.
All lanes : Anti-Eph receptor B1 + Eph receptor B2 antibody (ab61765) at 1/500 dilution
Lane 1 : Extracts from HepG2 cells.
Lane 2 : Extracts from HepG2 cells and the immunising peptide.
Predicted band size: 110 kDa
Observed band size: 110 kDa
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHB1/2 Antibody. The picture on the right is blocked with the synthesized peptide.
ab61765 has not yet been referenced specifically in any publications.