Overview

  • Product name

    Anti-EPHA10 antibody
  • Description

    Rabbit polyclonal to EPHA10
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 14 aa from near the N-terminus of Human EPHA10 (NP_001092909).

  • Positive control

    • 293 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 110 kDa.

Target

  • Function

    Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.
  • Tissue specificity

    Mainly expressed in testis.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Domain

    The protein kinase domain is predicted to be catalytically inactive.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Form

    Ephrin receptors, the largest subfamily of receptor tyrosine kinases, and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells. There are 3 isoforms produced by alternative splicing. Isoform 2 known as Epha10s, Isoform 3 known as Epha10*.
  • Alternative names

    • EPH receptor A10 antibody
    • EPHA 10 antibody
    • Epha10 antibody
    • EphA10s protein antibody
    • EPHAA_HUMAN antibody
    • Ephrin type A receptor 10 antibody
    • Ephrin type-A receptor 10 antibody
    • FLJ16103 antibody
    • FLJ33655 antibody
    • MGC43817 antibody
    see all

Images

  • Lane 1 : Anti-EPHA10 antibody (ab106437) at 1 µg/ml
    Lane 2 : Anti-EPHA10 antibody (ab106437) at 2 µg/ml

    All lanes : 293 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 110 kDa

References

This product has been referenced in:

  • Zhang J  et al. Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo. Drug Deliv 25:723-737 (2018). Read more (PubMed: 29513049) »
See 1 Publication for this product

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