Key features and details
- Rabbit polyclonal to Ephexin-5
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-Ephexin-5 antibody
See all Ephexin-5 primary antibodies
DescriptionRabbit polyclonal to Ephexin-5
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Human
Recombinant fragment corresponding to Human Ephexin-5 aa 464-667.
Database link: O94989
- Mouse liver whole cell lysate.
General notesKeep as concentrated solution.
Previously labelled as Rho guanine exchange factor 15.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78% PBS, 1% BSA, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab127704 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 93 kDa.|
FunctionSpecific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Tissue specificityExpressed in the vascular smooth muscle of coronary artery.
Sequence similaritiesContains 1 DH (DBL-homology) domain.
modificationsPhosphorylated on tyrosine residues upon EFNA1 stimulation.
Phosphorylation at Tyr-353 by EPHB2 triggers ubiquitination and degradation by the proteasome which promotes EFNB1-dependent synapse formation.
Cellular localizationCell projection > dendrite. Expressed exclusively in dendrites of the developing hippocampus.
- Information by UniProt
- ARGEF15 antibody
- ARHGEF15 antibody
- ARHGF_HUMAN antibody
ab127704 has not yet been referenced specifically in any publications.