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ChIC/CUT&RUN-seq validated recombinant antibodies

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  • Epigenetics resources
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      • Epigenetics protocols
        • ChIC/CUT&RUN-seq protocol
        • View all ChIC/CUT&RUN-seq products

          Achieve reliable, reproducible results in ChIC/CUT&RUN-seq application with our batch-to-batch consistent recombinant antibodies cross-validated in ChIC/CUT&RUN-seq with a pAG-MNase enzyme.  

          Browse all our ChIC/CUT&RUN-seq validated recombinant antibodies 

          Published January 14, 2022

          Contents

          • Benefits of transitioning from ChIP-seq to ChIC/CUT&RUN-seq technique
          • Our end-to-end solution for ChIC/CUT&RUN-seq
          • Consistent ChIC/CUT&RUN-seq data comparable with ChIP-seq results

          Benefits of transitioning from ChIP-seq to ChIC/CUT&RUN-seq technique

          ChIC/CUT&RUN-seq is a next-generation sequencing technique, which is faster and more cost-effective than the traditional ChIP-seq. Compared to ChIP-seq, the ChIC/CUT&RUN-seq technique requires only a fraction of starting material but provides a better signal-to-noise ratio. Furthermore, the ChIC/CUT&RUN-seq protocol is compatible with automation and a large choice of targets and antibodies, allowing for more versatility in experimental design.

          To learn more about different epigenetics techniques and relevant products, explore our Epigenetics hub for protocols, guides, webinars, and more.

          Our end-to-end solution for ChIC/CUT&RUN-seq

          To provide you with efficient and consistent reagents for ChIC/CUT&RUN-seq, we offer you our end-to-end solution including:

          • Recombinant monoclonal antibodies validated in ChIC/CUT&RUN-seq with detailed data
          • pAG-MNase enzyme (ab285373) cross-validated with our antibodies

          All our antibodies for ChIC/CUT&RUN-seq are produced recombinantly to guarantee excellent batch-to-batch consistency and long-term security of supply. Furthermore, these antibodies are routinely cross-validated with our pAG-MNase enzyme to ensure their compatibility and reliable performance.

          Explore our top ChIC/CUT&RUN-seq validated recombinant antibodies:

          Anti-CTCF (ab188408) |Anti-TATA binding protein TBP (ab220788) |Anti-H3K4me (ab176877) |Anti-H3K4me2 (ab176878)  |Anti-H3K4me3 (ab213224) 

          Browse all our ChIC/CUT&RUN-seq validated recombinant antibodies


          Consistent ChIC/CUT&RUN-seq data comparable with ChIP-seq results

          To ensure you can easily make an informed decision when choosing antibodies for ChIC/CUT&RUN-seq, we strive to clearly show the consistency of ChIC/CUT&RUN-seq data to corresponding ChIP-seq data in the datasheets wherever applicable. Figures 1 and 2 demonstrate similar sequencing results obtained with ChIC/CUT&RUN-seq and ChIP-seq protocols for anti-CTCF antibody (ab188408) (Fig. 1) and anti-H3K4me3 antibody (ab213224) (Fig. 2). 

          Figure 1. ChIC/CUT&RUN sequencing for anti-CTCF antibody [EPR18253] - ChIP Grade (ab188408). 

          Figure 2. ChIC/CUT&RUN sequencing for anti-H3K4me3 antibody [EPR20551-225] - ChIP Grade (ab213224).

          Browse all our ChIC/CUT&RUN-seq validated recombinant antibodies


          To learn more about our ChIC/CUT&RUN-seq validated antibodies, download our brochure.





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