Anti-Epiphycan antibody (ab122449)
Key features and details
- Rabbit polyclonal to Epiphycan
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Epiphycan antibody -
Description
Rabbit polyclonal to Epiphycan -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment: LRDNKIRQLP ELPTTLTFID ISNNRLGRKG IKQEAFKDMY DLHHLYLTDN NLDHIPLPLP ENLRALHLQN NNILEMHEDT FCNV, corresponding to amino acids 198-281 of Human Epiphycan.
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Positive control
- Human testis tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122449 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization. -
Tissue specificity
Cartilage, ligament, and placenta. -
Sequence similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain. -
Post-translational
modificationsThe O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64. -
Cellular localization
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 1833 Human
- Entrez Gene: 13516 Mouse
- Entrez Gene: 314772 Rat
- SwissProt: Q99645 Human
- SwissProt: P70186 Mouse
- Unigene: 435680 Human
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Alternative names
- Dermatan sulfate proteoglycan 3 antibody
- DSPG3 antibody
- Epiphycan antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab122449 has not yet been referenced specifically in any publications.