Key features and details
- Rabbit polyclonal to ERAP2 - N-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-ERAP2 antibody - N-terminal
See all ERAP2 primary antibodies
DescriptionRabbit polyclonal to ERAP2 - N-terminal
Specificityab181404 is predicted to not cross-react with ARTS1 (ERAP1).
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human ERAP2 (N terminal). Peptide corresponds to 17 amino acids (NP_071745)
Database link: Q6P179
- Rat small intestine tissue and tissue lysate.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab181404 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 103 kDa (predicted molecular weight: 110 kDa).|
RelevanceERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys.
Cellular localizationEndoplasmic reticulum membrane; Single-pass type II membrane protein.
- Endoplasmic reticulum aminopeptidase 2 antibody
- L RAP antibody
- Leukocyte derived arginine aminopeptidase antibody
- LRAP antibody
Anti-ERAP2 antibody - N-terminal (ab181404) at 1 µg/ml + rat small intestine tissue lysate at 15 µg
Developed using the ECL technique.
Predicted band size: 110 kDa
Observed band size: 103 kDa why is the actual band size different from the predicted?
ab181404 has not yet been referenced specifically in any publications.