Overview

  • Product name

    Anti-ERAP2 antibody - N-terminal
    See all ERAP2 primary antibodies
  • Description

    Rabbit polyclonal to ERAP2 - N-terminal
  • Host species

    Rabbit
  • Specificity

    ab181404 is predicted to not cross-react with ARTS1 (ERAP1).
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ERAP2 (N terminal). Peptide corresponds to 17 amino acids (NP_071745)
    Database link: Q6P179

  • Positive control

    • Rat small intestine tissue and tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab181404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 103 kDa (predicted molecular weight: 110 kDa).

Target

  • Relevance

    ERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys.
  • Cellular localization

    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • Database links

  • Alternative names

    • Endoplasmic reticulum aminopeptidase 2 antibody
    • L RAP antibody
    • Leukocyte derived arginine aminopeptidase antibody
    • LRAP antibody

Images

  • Anti-ERAP2 antibody - N-terminal (ab181404) at 1 µg/ml + rat small intestine tissue lysate at 15 µg

    Developed using the ECL technique.

    Predicted band size: 110 kDa
    Observed band size: 103 kDa
    why is the actual band size different from the predicted?

References

ab181404 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181404.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up