Key features and details
- Goat polyclonal to Erbin
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Erbin antibody
See all Erbin primary antibodies
DescriptionGoat polyclonal to Erbin
Tested applicationsSuitable for: ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Rat
Synthetic peptide from C terminal amino acids of Human Erbin.
- Human Colon tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab124653 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionActs as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state.
Tissue specificityHighly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine.
Sequence similaritiesBelongs to the LAP (LRR and PDZ) protein family.
Contains 17 LRR (leucine-rich) repeats.
Contains 1 PDZ (DHR) domain.
Cellular localizationCell junction > hemidesmosome. Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane.
- Information by UniProt
- Densin-180-like protein antibody
- Erbb2-interacting protein antibody
- Erbb2ip antibody
ab124653 has not yet been referenced specifically in any publications.