Anti-ERC2 antibody [EPR9419] (ab170862)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-ERC2 antibody [EPR9419]
See all ERC2 primary antibodies -
DescriptionRabbit monoclonal [EPR9419] to ERC2
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Host speciesRabbit
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Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivityReacts with: Mouse, Rat, Human
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Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ERC2 aa 900 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
Database link: O15083 -
Positive control
- Fetal brain and SH-SY5Y lysates.
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General notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant -
PurityTissue culture supernatant
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ClonalityMonoclonal
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Clone numberEPR9419
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IsotypeIgG
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Research areas
Associated products
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab170862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/10000. Predicted molecular weight: 111 kDa. |
Target
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FunctionThought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
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Cellular localizationCytoplasm. Cell junction > synapse. Cell junction > synapse > synaptosome. Cytoplasm > cytoskeleton. In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density.
- Information by UniProt
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Database links
- Entrez Gene: 26059 Human
- Entrez Gene: 238988 Mouse
- Entrez Gene: 259269 Rat
- SwissProt: O15083 Human
- SwissProt: Q6PH08 Mouse
- SwissProt: Q8K3M6 Rat
- Unigene: 476389 Human
- Unigene: 318004 Mouse
see all -
Alternative names
- Cast antibody
- CAST1 antibody
- CAZ-associated structural protein 1 antibody
see all
Images
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![Western blot - Anti-ERC2 antibody [EPR9419] (ab170862)](https://www.abcam.com/ps/products/170/ab170862/Images/ab170862-170725-ab1708621.jpg)
Western blot - Anti-ERC2 antibody [EPR9419] (ab170862)All lanes : Anti-ERC2 antibody [EPR9419] (ab170862) at 1/1000 dilution
Lane 1 : Fetal brain lysate
Lane 2 : SH-SY5Y lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 111 kDa
Protocols
Datasheets and documents
References
ab170862 has not yet been referenced specifically in any publications.
