Overview

  • Product name

    Ergosterol, Provitamin of Calciferol
  • Description

    Provitamin of Calciferol
  • Biological description

    Provitamin of Calciferol (ab143588). Component of plant and fungi cell walls. Regulates membrane fluidity and permeability. Shows moderate apoptotic activity. Shows anti-inflammatory and diuretic effects in vivo.
  • Purity

    > 97%
  • CAS Number

    57-87-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-Dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol

  • Molecular weight

    396.65
  • Molecular formula

    C28H44O
  • PubChem identifier

    444679
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in chloroform to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1[C@@H](CC2[C@](C1)([C@]3(C(=CC=2)[C@]4([C@](CC3)([C@@](CC4)([C@@H](/C=C/[C@@H](C(C)C)C)C)[H])C)[H])[H])C)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chen DQ  et al. Cloud-point extraction combined with liquid chromatography for the determination of ergosterol, a natural product with diuretic activity, in rat plasma, urine, and faeces. J Anal Methods Chem 2013:479056 (2013). Read more (PubMed: 23691436) »
  • Iwaki T  et al. Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe. Microbiology 154:830-41 (2008). Read more (PubMed: 18310029) »
  • Wiseman H Vitamin D is a membrane antioxidant. Ability to inhibit iron-dependent lipid peroxidation in liposomes compared to cholesterol, ergosterol and tamoxifen and relevance to anticancer action. FEBS Lett 326:285-8 (1993). Read more (PubMed: 8325381) »
  • Tsugawa N  et al. Metabolism of orally administered ergosterol and 7-dehydrocholesterol in rats and lack of evidence for their vitamin D biological activity. J Nutr Sci Vitaminol (Tokyo) 38:15-25 (1992). Read more (PubMed: 1629783) »

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