Anti-ESM1 antibody (ab224591)
Key features and details
- Rabbit polyclonal to ESM1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ESM1 antibody
See all ESM1 primary antibodies -
Description
Rabbit polyclonal to ESM1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human ESM1 aa 1 to the C-terminus.
Database link: Q9NQ30 -
Positive control
- IHC: Human lung tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab224591 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/20 - 1/200.
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Notes |
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IHC-P
1/20 - 1/200. |
Target
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Function
May have potent implications in lung endothelial cell-leukocyte interactions. -
Tissue specificity
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney. -
Sequence similarities
Contains 1 IGFBP N-terminal domain. -
Post-translational
modificationsMay contain intrachain disulfide bonds. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 11082 Human
- Omim: 601521 Human
- SwissProt: Q9NQ30 Human
- Unigene: 129944 Human
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Alternative names
- Endocan antibody
- Endothelial cell specific molecule 1 antibody
- Endothelial cell-specific molecule 1 antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab224591 has been referenced in 4 publications.
- Li YK et al. Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance. Int J Biol Sci 19:258-280 (2023). PubMed: 36594088
- Lee YH et al. Endocan as a marker of microvascular inflammation in kidney transplant recipients. Sci Rep 9:1854 (2019). PubMed: 30755622
- Xie X et al. ALDH1A3 Regulations of Matricellular Proteins Promote Vascular Smooth Muscle Cell Proliferation. iScience 19:872-882 (2019). PubMed: 31513972
- Cai H et al. Exosomal MicroRNA-9-3p Secreted from BMSCs Downregulates ESM1 to Suppress the Development of Bladder Cancer. Mol Ther Nucleic Acids 18:787-800 (2019). PubMed: 31734559