Overview

  • Product name

    Anti-ESRP1 antibody - C-terminal
  • Description

    Rabbit polyclonal to ESRP1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment within Human ESRP1 (C terminal). The exact sequence is proprietary.
    Database link: Q6NXG1

  • Positive control

    • WB: HCT 116 nuclear and whole cell extract.
  • General notes

     This product was previously labelled as RBM35A

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 76 kDa.

Target

  • Function

    mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
  • Tissue specificity

    Epithelial cell-specific.
  • Sequence similarities

    Belongs to the ESRP family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Epithelial splicing regulatory protein 1 antibody
    • Esrp1 antibody
    • ESRP1_HUMAN antibody
    • FLJ20171 antibody
    • RBM35A antibody
    • RMB35A antibody
    • RNA binding motif protein 35A antibody
    • RNA-binding motif protein 35A antibody
    • RNA-binding protein 35A antibody
    see all

Images

  • All lanes : Anti-ESRP1 antibody - C-terminal (ab229591) at 1/1000 dilution

    Lane 1 : HCT 116 (Human colorectal carcinoma cell line) whole cell extract
    Lane 2 : HCT 116 (Human colorectal carcinoma cell line) nuclear extract

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 76 kDa



    7.5% SDS-PAGE gel.

References

ab229591 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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